We use the amphibian Xenopus laevis as a comparative vertebrate model to uncover mechanisms linking immunity, development and tissue physiology
Development & Homeostasis: How are immune cells generated, maintained, and functionally specialized throughout vertebrate development?
Tissue Homeostasis, Repair & Regeneration: How do immune cells communicate with other cell types to dictate immune responses, scar formation, wound repair, or regeneration?
Host-Microbe Interactions: How do tissues balance protection from pathogens with tolerance of their microbial environment?
Development & Homeostasis: How are immune cells generated, maintained, and functionally specialized throughout vertebrate development?
Tissue Homeostasis, Repair & Regeneration: How do immune cells communicate with other cell types to dictate immune responses, scar formation, wound repair, or regeneration?
Host-Microbe Interactions: How do tissues balance protection from pathogens with tolerance of their microbial environment?